In an episode chock full of amazing scenes, this one is my favourite:
I identified so much with Sam. My mum was diagnosed with Early Onset Alzheimers in her early 50's and I was in my late teens. Living with her and watching as the disease slowly took away a lot of her memories (like Dean, she was well aware of what was happening to her) was worse than when she passed away a few years later. It was heartbreaking knowing there was nothing any of us could do except be there with her. I'll be forever grateful that she at least remembered Dad, me and my brothers right up until the end.